Sequence without tags (AA 1-74): MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNIVNVSLVKPSFYVYSRVKNLNSSRVPDLLV
Expression Host:E. coli
Formulation: PBS, pH 7,4
Format: Liquid, stored and shipped at -80°C
Purity: > 85% as determined by SDS-PAGE
The SARS-CoV-2 virus belongs to the group of enveloped viruses, this means the virus buds from the cell membrane and borrows a part of the membrane for its envelope. The presence of this additional barrier is essential for the stability of the virus, it protects it against external and environmental influences like disinfecting agents, it also facilitates the entering into the host cell. Embedded in the host´s membrane around the virus are viral proteins like the spike protein trimer as well as an additional envelope (E) protein, whose function is not finally solved. It is suspected to establish the contact between the envelope membrane and the capsid. With only 75 AA it is rather small compared to the much larger spike protein complex (1273 AA). It is embedded in the virus envelope towards the outside and contacts the S and M proteins to guarantee the stability of the virus particle.