Follistatin-related protein 3

• Species: Homo sapiens, human
• Tags: His-Tag, C-terminal
• Sequence without tags (AA 27-263):
  

  MGSGNPAPGGVCWLQQGQEATCSLVLQTDVTRAECCASGNIDTAWSNLTHPGNKINLLGF
  LGLVHCLPCKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDEC
  ELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSP
  GQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPEEPPGGESAEEEENFV

• Expression Host: human, HEK293
• Formulation: PBS; pH 7.4.
• Format: Liquid, stored and shipped at -80°C
• Purity: > 80% as determined by SDS-PAGE

Human follistatin-related protein 3 (FSTL3) is a secrected glycoprotein, which is structurally and functionally related to the activin-binding protein follistatin. It is expressed in various organs and tissues such as placenta, testis, heart and lung and plays an important role in a variety of cellular functions. By binding to activin-A and myostatin, both members of the TGF-ß family, FSTL3 antagonizes their cellular activity, thereby regulating physiological processes including cell differentiation and proliferation, metabolic pathways, inflammation and tumor development.

SDS-PAGE/Coll. Coomassie	Histogram of marked lane in gel picture

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