SARS-CoV-2 S-Protein Beta, B.1.351 (South Africa), His-Tag, Trimer

€780.00

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SKU: P2020-044 trenzyme

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Recombinant Spike protein of SARS-CoV-2 Beta variant, B.1.351 (South Africa) with C-terminal Strep- and His-Tag as a stabilized trimer and with deletion of the internal Furin-site.
The Beta variant is characterized by the following mutations: L18F, D80A, D215G, R246I, K417N, E484K, N501Y, D614G, A701V. Some of these mutations are affecting the receptor binding domain (RBD) of the spike protein, which the virus uses to bind to human cells receptors and enter them. Due to the mutations, the virus is allowed to bind with higher affinity to human ACE2 receptor which results in increased transmissibility of the SARS-CoV-2 virus.

Overview

  • Product Name: SARS-CoV-2 S protein (N501Y, E484K, K417N), His-Tag, Trimer
  • Catalog No.: P2020-044
  • RefSeq Links: NC_045512.2; MN908947.3; YP_009724390.1; QHD43416.1; GeneID: 43740568; UniProt: P0DTC2
  • Synonyms: SARS-CoV-2; coronavirus; SARS-CoV-2 spike protein; S glycoprotein; spike glycoprotein; 2019-nCoV; COVID-2019; COVID-19; Beta-variant; B.1.351; B1351; 20H/501Y.V2

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