SARS-CoV-2 S1 (RBD) B.1.141/B.1.258 (Scotland/U.K.)


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SKU: P2020-034 trenzyme

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Recombinant protein of the receptor binding domain (RBD), Mutant (N439K) of SARS-CoV-2 (COVID-2019) Spike S1 from Wuhan pneumonia virus with C-terminal His-Tag. The N439K mutation, lineage B.1.141/B.1.258 (Scotland/UK)), is known as the second common mutation in the RBD of SARS-CoV-2 and binds with high affinity to human ACE2 receptor. The mutation may result in immune escape from a panel of neutralizing monoclonal antibodies and polyclonal sera of persons recovered from infection.


  • Product Name: SARS-CoV-2 (COVID-19) Spike S1 Protein (RBD, Mutant (N439K))
  • Catalog No.: P2020-034
  • RefSeq Links: NC_045512.2; MN908947.3; YP_009724390.1; QHD43416.1; GeneID: 43740568; UniProt: P0DTC2
  • Synonyms: SARS-CoV-2; coronavirus; SARS-CoV-2 spike RBD; SARS-CoV-2 spike protein; 2019-nCoV; COVID-2019; COVID-19; RBD (N439K); B.1.141; B1141; Scottish Variant; Scottish lineage; B.1.258; B1258; U.K. Variant; U.K. lineage