SARS-CoV-2 S1 (RBD) Delta plus B.1.617.2 (India), GFP/His-Tag

€470.00

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SKU: P2020-055 trenzyme

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Recombinant protein of the receptor binding domain (RBD) Mutant (K417N, L452R, T478K) of SARS-CoV-2 (COVID-2019) Spike S1 from Wuhan pneumonia virus with C-terminal GFP/His-Tag. The mutations K417N, L452R and T478K are characteristic for the SARS-CoV-2 virus variant AY.1/AY.2/AY.3 which were initially reported in America with a single reclassified case in the UK and India in August 2021. AY.1/AY.2/AY.3 are also known as Delta Plus variant, sub-lineages of Delta. The mutations are affecting the receptor binding domain (RBD) of the spike protein, which the virus uses to bind to human cells receptors and enter them. Due to the mutations, the virus is allowed to bind with higher affinity to human ACE2 receptor which results in increased transmissibility of the SARS-CoV-2 virus.

Overview

  • Product Name: SARS-CoV-2 S1 (RBD) (K417N, L452R, T478K), GFP/His-Tag (cleavable)
  • Catalog No.: P2020-055
  • RefSeq Links: NC_045512.2; MN908947.3; YP_009724390.1; QHD43416.1; GeneID: 43740568; UniProt: P0DTC2
  • Synonyms: SARS-CoV-2; coronavirus; SARS-CoV-2 spike RBD; SARS-CoV-2 spike protein; 2019-nCoV; COVID-2019; COVID-19; RBD (K417N, L452R, T478K); Delta Plus; B.1.617.2; Indian Variant; India; K417N; L452R; T478K