SARS-CoV-2 S1 (RBD) Lambda C.37 (Peru), GFP/His-Tag


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SKU: P2020-054 trenzyme

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Recombinant protein of the receptor binding domain (RBD), Mutant (L452Q-F490S) of SARS-CoV-2 (COVID-2019) Spike S1 from Wuhan pneumonia virus with C-terminal His/GFP-Tag. The mutations L452Q-F490S are characteristic for the SARS-CoV-2 virus variant C.37 emerged in South America (Peru) in late 2020. C.37 is classified as Variant of Interest (VOI) and also known as Lambda variant. The mutations are affecting the receptor binding domain (RBD) of the spike protein, which the virus uses to bind to human cells receptors and enter them. The variant may result in an increased transmissibility and viral fitness. The F490S mutation together with other mutations at position L452, has been associated with resistance to neutralization.


  • Product Name: SARS-CoV-2 S1 (RBD) (L452Q, F490S), GFP/His-Tag (cleavable)
  • Catalog No.: P2020-054
  • RefSeq Links: NC_045512.2; MN908947.3; YP_009724390.1; QHD43416.1; GeneID: 43740568; UniProt: P0DTC2
  • Synonyms: SARS-CoV-2; coronavirus; SARS-CoV-2 spike RBD; SARS-CoV-2 spike protein; 2019-nCoV; COVID-2019; COVID-19; RBD (L452Q, F490S); GR/452Q.V1; 21G; Lambda; C.37; B.; South America Variant; Peru; F490S; L452Q