SARS-CoV-2 S1 (RBD) Mu B.1.621 (Columbia), GFP/His-Tag


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SKU: P2020-057 trenzyme

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Recombinant protein of the receptor binding domain (RBD), Mutant (R346K, E484K, N501Y) of SARS-CoV-2 (COVID-2019) spike S1 from Wuhan pneumonia virus with C-terminal GFP/His tag. The mutations R346K, E484K, and N501Y are identified in the SARS-CoV-2 virus variant B.1.621, which emerged in South America and was first reported in Colombia in January 2021. B.1.621 classified as Variant of Interest (VOI) and also known as Mu variant. The mutations are located in the RBD domain of SARS-CoV-2 and bind with high affinity to the human ACE2 receptor. The Colombian Mu variant initiates infection in the upper respiratory tract and is considered as the fastest spreading variant and one of the most dangerous.


  • Product Name: SARS-CoV-2 S1 (RBD) (R346K, E484K, N510Y), GFP/His-Tag (cleavable)
  • Catalog No.: P2020-057
  • RefSeq Links: NC_045512.2; MN908947.3; YP_009724390.1; QHD43416.1; GeneID: 43740568; UniProt: P0DTC2
  • Synonyms: SARS-CoV-2; coronavirus; SARS-CoV-2 spike RBD; SARS-CoV-2 spike protein; 2019-nCoV; COVID-2019; COVID-19; RBD (R346K, E484K, N510Y); Mu; B.1.621; Columbian Variant; Columbia; R346K; E484K; N510Y