Recombinant protein of the receptor binding domain (RBD) of SARS-CoV-2 (COVID-2019) spike S1 from Wuhan pneumonia virus, Omicron variant BA.1 with a high number of mutations (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H). Protein with C-terminal GFP/His tag.
The variant also known as PANGO lineage B.1.1.529 BA.1 has an unusually large number of mutations, several of which are novel and several of which affect the spike protein used for most vaccine targeting at the time of its discovery. This exceptional level of variation has led to concerns regarding transmissibility, immune system evasion, and vaccine resistance.
Therefore, the WHO designated it as a variant of concern. The GISAID project has assigned it the clade identifier GR/484A and the Nextstrain project has assigned it the clade identifier 21K.
Product Name: SARS-CoV-2 S1 (RBD) (Omicron Variant B.1.1.529 BA.1), GFP/His-tag (cleavable)
Catalog No.: P2020-061
RefSeq Links: NC_045512.2; MN908947.3; YP_009724390.1; QHD43416.1; GeneID: 43740568; UniProt: P0DTC2; Genebank Accession: #QHD43416.1
Synonyms: SARS-CoV-2; coronavirus; SARS-CoV-2 spike RBD; SARS-CoV-2 spike protein; 2019-nCoV; COVID-2019; COVID-19; RBD (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H); Omicron; B.1.1.529; South Africa; Botswana; GISAID clade: GISAID clade GR/484A; Nextstrain clade 21K; variant of concern (VOC)